Which two combined drugs are known to cause convulsion and hypertension?

The correct pairing is magnesium sulfate and hydralazine, as both of these medications can contribute to convulsions and hypertension under certain conditions. Magnesium sulfate is often used to manage conditions such as eclampsia and can cause adverse effects when not carefully monitored, including respiratory depression and changes in neurological status that could lead to convulsions. Hydralazine, on the other hand, is an antihypertensive that can induce hypotension through vasodilation, but abrupt withdrawal or inadequate dosing can lead to rebound hypertension. The combination of these two drugs in specific patient populations, particularly those with a history of seizures or hypertensive crises, can elevate the risk of both convulsions and increased blood pressure.

In contrast, the other options present medications that are typically utilized for different therapeutic goals. Insulin and metformin both manage diabetes effectively but are not related to the induction of convulsions or significant elevations in blood pressure. Atenolol, a beta-blocker, and lisinopril, an ACE inhibitor, work to lower blood pressure and do not typically cause convulsions. Lastly, furosemide, a loop diuretic, and spironolactone, a potassium-sparing diuretic, are commonly used