Which category of medication is typically considered the safest during pregnancy?

Category A medications are considered the safest during pregnancy because they have been extensively studied in pregnant women and have not shown any risk to the fetus in the first trimester or later trimesters. This category includes drugs that have well-controlled studies indicating that there is a low likelihood of adverse effects on fetal development. Healthcare providers often recommend these medications for pregnant women when necessary, as they have the most favorable safety profile.

In contrast, Category B medications may not have enough studies in humans to fully determine their safety, but animal studies have not demonstrated any risk, making them generally acceptable with caution. Category C medications have shown adverse effects in animal studies, and their effects in humans are not well understood, which makes them less preferable than Category A. Category D medications have evidence of human fetal risk but may be prescribed in certain situations if the benefits outweigh the risks.