What is the main concern with Category C pharmacological agents during pregnancy?

The main concern with Category C pharmacological agents during pregnancy is that only animal studies indicate potential risks. This category includes drugs for which there is not enough well-controlled data in humans to fully assess their safety. While animal studies may suggest that there could be risks to the developing fetus, human data is insufficient to draw definitive conclusions. This lack of definitive human data necessitates a cautious approach by healthcare providers when considering the use of these medications during pregnancy.

Category C agents are prescribed only when the potential benefit justifies the potential risk to the fetus. Therefore, the focus is on the interpretation of animal study results, which show a risk that has not been confirmed in human studies. Other answers may imply more definitive conclusions about safety or risks that are not supported by the classification of Category C. Understanding this classification is crucial for making informed decisions about medication usage during pregnancy.